An efficient etherification of Ginkgol biloba extracts with fewer side effects in a micro-flow system
- Yin-Lin Qina
- Wei Hea
- Mei Sub
- Zheng Fangc
- Ping-Kai Ouyanga
- Kai Guoa,d
- a College of Biotechnology and Pharmaceutical Engineering, Nanjing Technology University, Nanjing 210009, China
- b Jiangsu Carephar Pharmaceutical Co., Ltd., Nanjing 210014, China
- c School of Pharmaceutical, Nanjing Technology University, Nanjing 210009, China
- d State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Technology University, Nanjing 211816, ChinaRead the publication that featured this abstract
In this study, etherification of ginkgolide B and dimethylaminoethyl chloride hydrochloride was investigated as a model reaction in a micro-flow system (MFS), providing the resulting ethers in high yield with fewer side effects. Meanwhile, this novel process in MFS worked well for other ginkgolides from Ginkgol biloba and halides, giving moderate yields.
The Vapourtec R-Series is, quite simply, unrivalled for flow chemistry
The R-Series is undoubtedly the most versatile, modular flow chemistry system available today.
The Vapourtec E-Series is the perfect introductory system for flow chemistry
- Robust :
- Easy to use :
The E-Series is a robust and affordable, entry level flow chemistry system designed for reliability and ease of use.