A laboratory-scale continuous flow chlorine generator for organic synthesis

    • Franz J. Straussa
    • David Cantillo*ab
    • Javier Guerrac
    • C. Oliver Kappe*ab
    • * Institute of Chemistry, University of Graz, NAWI Graz, Heinrichstrasse 28, Graz, Austria
    • a Research Center Pharmaceutical Engineering GmbH (RCPE), Inffeldgasse 13, 8010 Graz, Austria
    • b Crystal Pharma, Gadea Pharmaceutical Group, A Division of AMRI, Parque Tecnológico de Boecillo, Valladolid, Spain

    A simple continuous flow setup for the generation and use of elemental chlorine for organic synthesis has been developed. The chlorine generator is based on the reaction of HCl with NaOCl, generating NaCl and H2O as the only side products. As a proof-of-concept, the reactor has been applied for a variety of chlorinations and oxidations of organic compounds.

    Read the publication that featured this abstract

    Get in touch

    For more information on flow chemistry systems and services please use the contact methods below.

    Call us on +44 (0)1284 728659 or Email us

    Request a quote