A concise flow synthesis of indole-3-carboxylic ester and its derivatisation to an auxin mimic
Marcus Baumann, Ian R. Baxendale and Fabien Deplante
- Department of Chemistry, University of Durham, South Road, Durham, Durham, DH1 3LE, UKRead the publication that featured this abstract
An assembled suite of flow-based transformations have been used to rapidly scale-up the production of a novel auxin mimic-based herbicide which was required for preliminary field trials. The overall synthetic approach and optimisation studies are described along with a full description of the final reactor configurations employed for the synthesis as well as the downstream processing of the reaction streams.
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