A Bifurcated Pathway to Thiazoles and Imidazoles Using a Modular Flow Microreactor

Added on:
11 Sep, 2008

A scalable method for the preparation of 4,5-disubstituted thiazoles and imidazoles as distinct regioisomeric products using a modular flow microreactor has been devised. The process makes use of microfluidic reaction chips and packed immobilized-reagent columns to effect bifurcation of the reaction pathway.

  • Ian R. Baxendale
  • Steven V. Ley
  • Christopher D. Smith
  • Lucia Tamborini
  • Ana-Florina Voica
  • Innovative Technology Centre, Cambridge, UK
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