Electrochemical Cyclopropanation of 1, 3-Dialkyl Bromides

An electrochemical synthesis of mono- and 1,1-disubstituted cyclopropanes has been demonstrated. Readily available 1,3-dialkyl bromides were used as starting materials, and the method was enabled by the incorporation of a sacrificial reductant along with cost-effective cathode and anode materials. The need for a divided cell and the use of hazardous or expensive electrodes were eliminated, facilitating the adaptation of the protocol to a continuous flow system. Additionally, an alternative protocol employing a simple sacrificial anode was described.

• Charvet, S
• Jacob, C
• Dietsch, A
• Tintori, G
• Echeverria, P
• Vantourout, J

• CNRS, INSA, CPE-Lyon, ICBMS, UMR 5246, Bâtiment LEDERER, Univ Lyon, Université Lyon 1, 1 rue Victor Grignard, 69622 Villeurbanne Cedex, France

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