Carbonylations in flow: tube-in-tube reactor vs. gas-liquid slug flow

In order to improve the performance of carbonylation reactions in flow Ładosz et al. compared the tube-in-tube system to a gas-liquid two-phase setup. They  found that the two-phase slug flow reactor significantly improved the yield and throughput of the reactions tested.

• Ładosz, A
• Friedli, A
• Lhuillery, A
• Rueedi, G

• Chemistry Technologies, Department of Chemical Sciences, Idorsia Pharmaceuticals Ltd, Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland

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