Suzuki-Miyaura Cross-Coupling of Heteroaryl Halides and Arylboronic Acids in Continuous Flow
- Timothy Noël
- Andrew J. Musacchio
- Department of Chemistry, MIT, USARead the publication that featured this abstract
General continuous-flow conditions for the Suzuki–Miyaura cross-coupling of heteroaryl halides and (hetero)arylboronic acids have been developed. A wide range of heterobiaryl products is obtained in excellent yields (20 examples) employing low catalyst loadings (0.05–1.5 mol % Pd).
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