Flow platform for the synthesis of benzodiazepines
- Maria Ivanovaa
- Thomas Poissona
- Philippe Jubaulta
- Julien Legrosa
- aNormandie Univ, INSA Rouen, UNIROUEN, CNRS, COBRA, 76000, Rouen, FranceRead the publication that featured this abstract
Benzodiazepines possess a wide spectrum of valuable pharmacological effects and are among the leading drugs, commonly prescribed ones for various pathologies. Herein we describe the continuous flow synthesis of six benzodiazepines from aminobenzophenones: diazepam, fludiazepam, nordazepam, nitrazepam, clonazepam, oxazepam.
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