Flow platform for the synthesis of benzodiazepines

    • Maria Ivanovaa
    • Thomas Poissona
    • Philippe Jubaulta
    • Julien Legrosa
    • aNormandie Univ, INSA Rouen, UNIROUEN, CNRS, COBRA, 76000, Rouen, France

    Benzodiazepines possess a wide spectrum of valuable pharmacological effects and are among the leading drugs, commonly prescribed ones for various pathologies. Herein we describe the continuous flow synthesis of six benzodiazepines from aminobenzophenones: diazepam, fludiazepam, nordazepam, nitrazepam, clonazepam, oxazepam.

    Read the publication that featured this abstract

    Get in touch

    For more information on flow chemistry systems and services please use the contact methods below.

    Call us on +44 (0)1284 728659 or Email us