Fully Automated Continuous Flow Synthesis of 4,5-Disubstituted Oxazoles

Added on:
11 Oct, 2006

A multipurpose mesofluidic flow reactor capable of producing gram quantities of material has been developed as an automated synthesis platform for the rapid on-demand synthesis of key building blocks and small exploratory libraries. The reactor is configured to provide the maximum flexibility for screening of reaction parameters that incorporate on-chip mixing and columns of solid supported reagents to expedite the chemical syntheses.

  • Marcus Baumann
  • Ian R. Baxendale
  • Steven V. Ley
  • Christoper D. Smith
  • Geoffrey K. Tranmer
  • Innovative Technology Center, University of Cambridge
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