Application notes

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The following application notes show the range of synthesis that are possible with the Vapourtec system.

Direct electrochemical oxidation of 4- tert-butyltoluene

Controlled Environmentally Friendly Oxidation

Application Note 64 – August 2019

This application note demonstrates the use of the Vapourtec Ion electrochemical reactor for the direct oxidation of 4-tert-butyltoluene into 4-tert-butyl benzaldehyde dimethyl acetal. After optimization of this key reaction, the desired product was afforded in a yield of 88%.

Ion electrochemical reactor part numbers

Reductive Electro-Organic Synthesis

Application Note 63 – June 2019

We now present a new application note prepared from work undertaken by New Path Molecular Research Ltd. This research project uses the Vapourtec Ion electrochemical reactor for the reductive cross-electrophile coupling of organic halides, constructing a Csp2-Csp3 bond. After optimization of this key reaction, the desired product was afforded in a yield of 81%.